SOS1-IN-4 is a potent inhibitor of SOS1, exhibiting an IC50 of 56 nM for the KRAS-C12C/SOS1 interaction. This compound is instrumental in studies investigating the role of SOS1 in RAS signaling pathways. Its application is significant in cancer research, particularly in models where KRAS mutations contribute to tumorigenesis.
SOS1-IN-4 is a potent inhibitor of SOS1, exhibiting an IC50 of 56 nM for the KRAS-C12C/SOS1 interaction. This compound is instrumental in studies investigating the role of SOS1 in RAS signaling pathways. Its application is significant in cancer research, particularly in models where KRAS mutations contribute to tumorigenesis.
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