SOS1-IN-9 is a selective inhibitor of SOS1, demonstrating an IC50 of 116.5 nM for the SOS1-KRAS G12C complex. This compound plays a crucial role in inhibiting SOS1-mediated signaling pathways, making it a valuable tool for research into KRAS-driven cancers. Its application extends to studies aimed at elucidating the mechanisms of oncogenic signaling and developing targeted therapeutic strategies.
SOS1-IN-9 is a selective inhibitor of SOS1, demonstrating an IC50 of 116.5 nM for the SOS1-KRAS G12C complex. This compound plays a crucial role in inhibiting SOS1-mediated signaling pathways, making it a valuable tool for research into KRAS-driven cancers. Its application extends to studies aimed at elucidating the mechanisms of oncogenic signaling and developing targeted therapeutic strategies.
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