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SOS1 Ligand intermediate-4

Catalog No.: A63647
SOS1 Ligand
SOS1 Ligand intermediate-4 is a key ligand for SOS1, playing a crucial role in the development of PROTAC-based degradation systems targeting SOS1. This compound facilitates the synthesis of SOS1 degraders, which can be employed in research related to targeted protein degradation and the modulation of oncogenic signaling pathways. Its ability to selectively interact with SOS1 makes it a valuable tool for investigating cellular mechanisms and therapeutic strategies in cancer biology.
SOS1 Ligand intermediate-4 3036155-94-6 SOS1 Ligand
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSOS1 Ligand intermediate-4 is a key ligand for SOS1, playing a crucial role in the development of PROTAC-based degradation systems targeting SOS1. This compound facilitates the synthesis of SOS1 degraders, which can be employed in research related to targeted protein degradation and the modulation of oncogenic signaling pathways. Its ability to selectively interact with SOS1 makes it a valuable tool for investigating cellular mechanisms and therapeutic strategies in cancer biology.
Product Information
Catalog NumA63647
FormulaC28H34N8O
Molecular Weight498.62
CAS Number3036155-94-6
SMILESN#CC1=C(C)C([C@@H](C)NC2=NN=C(C)C3=C2C=C(N4CCN(C(C5CCNCC5)=O)CC4)N=C3)=CC=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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MAPK > SOS1