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SOS1 Ligand intermediate-6

Catalog No.: A65868
SOS1 Ligand Intermediate
SOS1 Ligand Intermediate-6 is a key precursor in the synthesis of SOS1 ligands, facilitating the development of targeted protein degradation technologies, such as PROTACs. This chemical reagent offers researchers a valuable tool for probing the SOS1 signaling pathway and potential therapeutic interventions. Its application in PROTAC synthesis broadens the scope for studying protein interactions and modulation in various biological systems.
SOS1 Ligand intermediate-6 3036156-01-8 SOS1 Ligand Intermediate
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSOS1 Ligand Intermediate-6 is a key precursor in the synthesis of SOS1 ligands, facilitating the development of targeted protein degradation technologies, such as PROTACs. This chemical reagent offers researchers a valuable tool for probing the SOS1 signaling pathway and potential therapeutic interventions. Its application in PROTAC synthesis broadens the scope for studying protein interactions and modulation in various biological systems.
Product Information
Catalog NumA65868
FormulaC22H26F2N6
Molecular Weight412.48
CAS Number3036156-01-8
SMILESCC1=NN=C(C2=C1C=NC(N3CCNCC3)=C2)N[C@@H](C4=CC=CC(C(F)F)=C4C)C
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MAPK > SOS1