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Sotrastaurin (AEB071)


PKC inhibitor

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Catalog No. A11554

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Sotrastaurin 5mg A11554-5

Regular Price: $120.00

Special Price: $108.00

Sotrastaurin 10mg A11554-10

Regular Price: $200.00

Special Price: $180.00

Sotrastaurin 25mg A11554-25

Regular Price: $380.00

Special Price: $342.00

Sotrastaurin 50mg A11554-50

Regular Price: $620.00

Special Price: $558.00

Sotrastaurin (AEB071) 10mM * 1mL in DMSO A11554-10mM-D

Regular Price: $164.00

Special Price: $147.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Sotrastaurin is a protein kinase C inhibitor for the prevention of transplant rejection and treatment of psoriasis.

Sotrastaurin (AEB071)

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Chemical Information

Catalog Num A11554
Actions Inhibitor
M. Wt 438.5
Formula C25H22N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 425637-18-9
Synonyms AEB 071, AEB-071

Biological Activity

Sotrastaurin is a protein kinase C inhibitor for the prevention of transplant rejection and treatment of psoriasis.
Target Value
PKCθki: 0.22nM
PKCβ1ki: 0.64nM
PKCαki: 0.95nM
PKCηki: 1.8nM
PKCδki: 2.1nM
PKCεki: 3.2nM


Solubility (25°C)* In vitro DMSO 87 mg/mL (198.41 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.56 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.81 mL 114.03 mL 228.05mL
0.5 mM 4.56 mL 22.81 mL 45.61 mL
1 mM 2.28 mL 11.4 mL 22.81 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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