SP/W 5186

Catalog No.: A65168
NO Donor Agent
SP/W-5186 is a nitric oxide (NO) donor agent featuring a cysteine structure. It exhibits protective effects on cardiac function, reduces myocardial damage, and enhances vascular endothelial integrity while also inhibiting inflammation and oxidative stress. SP/W-5186 is particularly relevant in studies of myocardial ischemia-reperfusion injury due to its capacity to mitigate oxidative damage caused by peroxynitrite (ONOO⁻).
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSP/W-5186 is a nitric oxide (NO) donor agent featuring a cysteine structure. It exhibits protective effects on cardiac function, reduces myocardial damage, and enhances vascular endothelial integrity while also inhibiting inflammation and oxidative stress. SP/W-5186 is particularly relevant in studies of myocardial ischemia-reperfusion injury due to its capacity to mitigate oxidative damage caused by peroxynitrite (ONOO⁻).
Product Information
Catalog NumA65168
FormulaC14H23N3O8S
Molecular Weight393.41
CAS Number139146-65-9
SMILESCC(CO[N+]([O-])=O)(C)C(N[C@H](C(OCC)=O)CSC(CNC(C)=O)=O)=O
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