Fig. 1 · Structure
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SPAA-52
LMW-PTP Inhibitor
SPAA-52 is a competitive and reversible inhibitor of low-molecular-weight protein tyrosine phosphatase (LMW-PTP), exhibiting an IC50 of 4 nM and a Ki of 1.2 nM. This compound has shown promise in biological research related to diabetes, aiding in the exploration of therapeutic avenues and the understanding of associated signaling pathways. Its potent inhibitory activity makes it a valuable tool for investigations into LMW-PTP's role in metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2837000-75-4 |
| Applications | LMW-PTP Inhibitor |
| Formula | C8H8Br2N2O4S |
| Molecular Weight | 388.03 |
| SMILES | O=S(O)(NC(NC1=CC(Br)=C(C)C(Br)=C1)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.