SPDP-Gly-Pro-NHS ester

Catalog No.: A94931
Biochemical Assay Reagent
SPDP-Gly-Pro-NHS ester is a biochemical assay reagent featuring both SPDP and NHS ester functionalities. The SPDP moiety serves as a reactive crosslinker, capable of forming covalent bonds with amines and thiols, facilitating intracellular crosslinking. The NHS ester component provides reactivity towards amines, enabling the formation of stable amide bonds. This versatile linker is ideal for applications in protein labeling, conjugation, and the study of protein interactions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSPDP-Gly-Pro-NHS ester is a biochemical assay reagent featuring both SPDP and NHS ester functionalities. The SPDP moiety serves as a reactive crosslinker, capable of forming covalent bonds with amines and thiols, facilitating intracellular crosslinking. The NHS ester component provides reactivity towards amines, enabling the formation of stable amide bonds. This versatile linker is ideal for applications in protein labeling, conjugation, and the study of protein interactions.
Product Information
Catalog NumA94931
FormulaC19H22N4O6S2
Molecular Weight466.53
CAS Number2655501-79-2
SMILESO=C(CCC1=O)N1OC([C@H]2N(CCC2)C(CNC(CCSSC3=CC=CC=N3)=O)=O)=O
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