Fig. 1 · Structure
Documents & Downloads
SPEN-IN-1
SPEN Inhibitor
SPEN-IN-1 is an inhibitor targeting SPEN, a protein factor involved in gene silencing. With a Kd value of 47 nM, SPEN-IN-1 demonstrates high selectivity for the RepA domain of Xist, a non-coding RNA prototype known for its GC-rich motifs. This compound is primarily utilized in research applications focused on understanding molecular mechanisms of gene regulation and potential therapeutic strategies targeting RNA interactions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2863686-82-0 |
| Applications | SPEN Inhibitor |
| Formula | C27H20N4O |
| Molecular Weight | 416.47 |
| SMILES | C1(C2=NC3=CC=CC=C3N2)=NNC4=C1C=C(C5=CC=CC(OCC6=CC=CC=C6)=C5)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.