Fig. 1 · Structure
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Spermine-d8 tetrahydrochloride
Stable Isotope
Spermine-d8 tetrahydrochloride is a deuterium-labeled form of spermine that serves as a stable isotope in biochemical research. This polyamine acts as a nitric oxide donor, influencing platelet activation in a concentration-dependent manner. Spermine-d8 exhibits multiple biological activities, including antioxidant and anti-inflammatory properties, while also demonstrating inhibitory effects on certain bacterial strains, such as Staphylococcus aureus. Additionally, it impacts immune responses by reversibly inhibiting DNA synthesis, mixed lymphocyte reactions, and the induction of cytolytic lymphocytes in murine spleen cell cultures.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1173022-85-9 |
| Applications | Stable Isotope |
| Formula | C10H22D8Cl4N4 |
| Molecular Weight | 356.23 |
| SMILES | NCCCNC(C(C(C(NCCCN)([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H].Cl.Cl.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.