Fig. 1 · Structure
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SPHINX
SRPK1 Inhibitor
SPHINX is a selective inhibitor of SRPK1, exhibiting an IC50 value of 0.58 μM. This compound effectively reduces choroidal neovascularization (CNV) in vivo, making it a valuable tool for studying age-related macular degeneration (AMD). Its mechanism of action and targeted inhibition provide significant insights into the molecular pathways influencing retinal vascular conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 848057-98-7 |
| Applications | SRPK1 Inhibitor |
| Formula | C17H17F3N2O3 |
| Molecular Weight | 354.32 |
| SMILES | O=C(C1=CC=C(C)O1)NC2=CC(C(F)(F)F)=CC=C2N3CCOCC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.