Fig. 1 · Structure

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Spire2-FMN2 PPI-IN-1

Spire2/FMN2 Inhibitor

Spire2-FMN2 PPI-IN-1 is a selective inhibitor designed to disrupt the Spire2-FMN2 protein-protein interaction, exhibiting an IC50 value of 62 μM. This compound shows specificity for KIND2 with a dissociation constant (Kd) of 87.7 μM, while exhibiting no inhibitory effect on KIND1. Spire2-FMN2 PPI-IN-1 serves as a valuable tool for researchers investigating the biological roles of the Spire2-FMN2 interaction and for the development of targeted chemical probes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1557337-03-7
Applications Spire2/FMN2 Inhibitor
Formula C11H12FN3
Molecular Weight 205.23
SMILES
FC1=CC=C2C(N=CC=C2NCCN)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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