Fig. 1 · Structure
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Spiroplatin
Antitumor Compound
Spiroplatin is a cisplatin congener with notable antitumor properties. It functions by binding to DNA and inducing cell cycle arrest, ultimately leading to apoptosis in cancer cells. This compound is primarily utilized in cancer research to investigate therapeutic strategies and mechanisms of drug resistance in various tumor models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 74790-08-2 |
| Applications | Antitumor Compound |
| Formula | C8H18N2O4PtS |
| Molecular Weight | 433.39 |
| Synonyms | TNO 6 |
| SMILES | O=S1([O-][Pt+2]2([NH2]CC3(C[NH2]2)CCCCC3)[O-]1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.