Fig. 1 · Structure
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Spisulosine
Anticancer Agent
Spisulosine is an anticancer agent derived from marine sources that exerts its effects by inhibiting tumor cell proliferation. It promotes intracellular ceramide accumulation and activates PKCζ, leading to enhanced apoptosis in both prostate cancer cell lines PC-3 and LNCaP. This compound is primarily utilized in research related to cancer biology and therapeutic development, exploring mechanisms of action in tumor suppression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 196497-48-0 |
| Applications | Anticancer Agent |
| Formula | C18H39NO |
| Molecular Weight | 285.51 |
| Synonyms | ES-285 |
| SMILES | C[C@H](N)[C@H](O)CCCCCCCCCCCCCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.