SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM.
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A19812
Formula
C16H15N5
Molecular Weight
277.32
CAS Number
1357349-91-7
SMILES
CC(C)N1C2=NC=NC(N)=C2C(C#CC3=CC=CC=C3)=N1
Synonyms
SPP 86; SPP86
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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