SQ-33600

Name: SQ-33600
Brand: Adooq Bioscience
SKU: A75672
Rating: 5 (288 reviews)

Catalog No.: A75672

HMG-CoA Reductase Inhibitor

SQ-33600 is an HMG-CoA reductase inhibitor that exhibits cholesterol-lowering activity. It demonstrates significant selectivity, showing a much stronger inhibitory effect on rat hepatocytes (IC50: 93 nM) compared to human skin fibroblasts (IC50: 14200 nM). This compound is valuable for research on hypercholesterolemia and related metabolic disorders.

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SQ-33600 133983-25-2 HMG-CoA Reductase Inhibitor

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Biological Activity

Description	SQ-33600 is an HMG-CoA reductase inhibitor that exhibits cholesterol-lowering activity. It demonstrates significant selectivity, showing a much stronger inhibitory effect on rat hepatocytes (IC50: 93 nM) compared to human skin fibroblasts (IC50: 14200 nM). This compound is valuable for research on hypercholesterolemia and related metabolic disorders.

Product Information

Catalog Num	A75672
Formula	C23H21FNNa2O5P
Molecular Weight	487.37
CAS Number	133983-25-2
SMILES	O=C(C[C@@H](CP(C#CC(N1C2=CC=C(C=C2)F)=C(C3=C1C=CC=C3)C(C)C)(O[Na])=O)O)O[Na]

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