Fig. 1 · Structure
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SR 49059
Vasopressin V1a Antagonist
SR 49059 is a selective antagonist of the vasopressin V1a receptor, exhibiting a Ki value of 1.4 nM. This potent, orally active compound is utilized primarily in research to investigate the physiological and pathophysiological roles of vasopressin signaling. Its application includes studies related to cardiovascular function, water homeostasis, and stress responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 150375-75-0 |
| Applications | Vasopressin V1a Antagonist |
| Formula | C28H27Cl2N3O7S |
| Molecular Weight | 620.50 |
| SMILES | ClC1=C([C@@]2(O)C3=CC(Cl)=CC=C3N(S(=O)(C4=CC(OC)=C(OC)C=C4)=O)[C@]2(C(N5[C@H](C(N)=O)CCC5)=O)[H])C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.