Fig. 1 · Structure
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SR 57227A free base
iGluR
SR 57227A free base is a selective inhibitor of NMDA receptor-mediated responses, primarily targeting ionotropic glutamate receptors (iGluRs). This compound has demonstrated significant antidepressant-like effects in rat models and has been shown to reduce isolation-induced aggressive behavior. Its unique mechanism makes it a valuable tool for studying the neuropharmacological effects related to mood disorders and aggression in behavioral research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 77145-51-8 |
| Applications | iGluR |
| Formula | C10H14ClN3 |
| Molecular Weight | 211.69 |
| SMILES | NC1CCN(CC1)C2=NC(Cl)=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.