Fig. 1 · Structure
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SRD5A1-IN-1
SRD5A1 Inhibitor
SRD5A1-IN-1 is a competitive and covalent inhibitor of steroid 5α-reductase type 1 (SRD5A1), exhibiting an IC50 of 1.44 µM. This compound effectively reduces dihydrotestosterone (DHT) levels through the modulation of SRD5A1 activity, resulting in the suppression of SRD5A1 protein expression. SRD5A1-IN-1 is valuable for research applications focused on androgen metabolism and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2279077-93-7 |
| Applications | SRD5A1 Inhibitor |
| Formula | C17H11F6NO3 |
| Molecular Weight | 391.26 |
| SMILES | O=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)/C=C/C2=CC(O)=C(C=C2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.