Fig. 1 · Structure
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SRI-37330
TXNIP Inhibitor
SRI-37330 is a potent inhibitor of thioredoxin-interacting protein (TXNIP). This compound effectively inhibits glucagon secretion and function, reduces hepatic glucose production, and mitigates hepatic steatosis. SRI-37330 is suitable for research applications focused on type 2 diabetes and related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2322245-42-9 |
| Applications | TXNIP Inhibitor |
| Formula | C16H19F3N4O2S |
| Molecular Weight | 388.41 |
| SMILES | CS(=O)(NCC1CN(C2=C3C=C(C(F)(F)F)C=CC3=NC=N2)CCC1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.