SRI-43265

Catalog No.: A57789
HuR Inhibitor
SRI-43265 is a selective inhibitor of human antigen R (HuR) dimerization, a crucial process impacting HuR's role in post-transcriptional regulation of target mRNAs. By disrupting HuR multimers, SRI-43265 demonstrates potential in studying cancer and inflammatory processes, where HuR's activity contributes to pathogenesis. This reagent is valuable for investigating the molecular mechanisms underlying these diseases and for exploring therapeutic strategies targeting HuR functions.
Grouped product items
Size Price Stock Qty
5mg
$140.00
In stock
10mg
$260.00
In stock
25mg
$520.00
In stock
50mg
$815.00
In stock
100mg
$1,270.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSRI-43265 is a selective inhibitor of human antigen R (HuR) dimerization, a crucial process impacting HuR's role in post-transcriptional regulation of target mRNAs. By disrupting HuR multimers, SRI-43265 demonstrates potential in studying cancer and inflammatory processes, where HuR's activity contributes to pathogenesis. This reagent is valuable for investigating the molecular mechanisms underlying these diseases and for exploring therapeutic strategies targeting HuR functions.
Product Information
Catalog NumA57789
FormulaC19H20N6O
Molecular Weight348.40
CAS Number2727872-88-8
SMILESCN(C1CCOCC1)C2=NN3C(C=C2)=NC=C3C4=CC=C5C(C=NN5)=C4
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