SRT 2183

Catalog No.: A12150

Sirtuin-1 (SIRT1) activator

SRT 2183

SRT 2183 Chemical Structure

CAS NO. 1001908-89-9

SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.

Availability: In stock

Package Price Qty
5 mg
$122.00
10 mg
$209.00
50 mg
$621.00
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Biological Activity

SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.34 mL 106.71 mL 213.42 mL
0.5 mM 4.27 mL 21.34 mL 42.68 mL
1 mM 2.13 mL 10.67 mL 21.34 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12150
Actions Activator
M. Wt 468.57
Formula C27H24N4O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1001908-89-9
Synonyms SRT2183, SRT-2183
SMILES O=C(NC1=C(C2=CN3C(SC=C3CN4CC[[email protected]@H](O)C4)=N2)C=CC=C1)C(C=C5)=CC6=C5C=CC=C6

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