Fig. 1 · Structure
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SS148
nsp14/nsp16 MTase Inhibitor
SS148 is a dual inhibitor targeting the nsp14/nsp16 methyltransferase complex. It demonstrates significant inhibitory activity against the nsp10–nsp16 interaction, with an IC50 of 1.2 μM. This compound is primarily used in research related to viral replication and the study of methyltransferase functions, providing insights into the molecular mechanisms of viral pathogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1985669-27-9 |
| Applications | nsp14/nsp16 MTase Inhibitor |
| Formula | C16H20N6O5S |
| Molecular Weight | 408.43 |
| SMILES | N#CC1=CN(C2=NC=NC(N)=C21)[C@@H]3O[C@H](CSCC[C@@H](C(O)=O)N)[C@@H](O)[C@H]3O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.