Fig. 1 · Structure
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SSR504734
GlyT1 Inhibitor
SSR504734 is a selective and reversible inhibitor of the glycine transporter 1 (GlyT1), demonstrating potent activity across human, rat, and mouse models with IC50 values of 18, 15, and 38 nM, respectively. This compound has been shown to exhibit anti-schizophrenia, anti-anxiety, and anti-depression effects, making it a valuable tool for research in neuropsychiatric conditions and related therapeutic studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 615571-23-8 |
| Applications | GlyT1 Inhibitor |
| Formula | C20H21Cl2F3N2O |
| Molecular Weight | 433.29 |
| SMILES | O=C(C1=C(C(C(F)(F)F)=CC=C1)Cl)N[C@H]([C@]2([H])CCCCN2)C3=CC=CC=C3.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.