ST1936 oxalate is a selective agonist of the 5-HT6 receptor, demonstrating high nanomolar affinity with a Ki value of 13 nM for the human receptor. It exhibits additional binding affinity for 5-HT7 and 5-HT2B receptors with Ki values of 168 nM and 245 nM, respectively, as well as moderate binding to α2 adrenergic receptors in both human and rat models (Ki of 300 nM). This compound is valuable for research applications focused on serotonergic signaling and its implications in neuropharmacology.
ST1936 oxalate is a selective agonist of the 5-HT6 receptor, demonstrating high nanomolar affinity with a Ki value of 13 nM for the human receptor. It exhibits additional binding affinity for 5-HT7 and 5-HT2B receptors with Ki values of 168 nM and 245 nM, respectively, as well as moderate binding to α2 adrenergic receptors in both human and rat models (Ki of 300 nM). This compound is valuable for research applications focused on serotonergic signaling and its implications in neuropharmacology.
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