Fig. 1 · Structure
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Starburst 1st generation (13.93% w/w in water)
Drug Delivery Vehicle
Starburst 1st Generation is a Polyamidoamine (PAMAM G1.0) dendrimer featuring amine termini, functioning as an efficient drug delivery vehicle. This dendrimer enhances the solubility of therapeutic agents such as 5-Fluorouracil and exhibits cytotoxic effects on AGS gastric adenocarcinoma cells. It serves as a valuable tool for in vitro studies focused on improving drug solubility and efficacy against cancer cell lines.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 142986-44-5 |
| Applications | Drug Delivery Vehicle |
| Formula | C62H128N26O12 |
| Molecular Weight | 1429.85 |
| Synonyms | PAMAM G1.0 |
| SMILES | O=C(CCN(CCC(NCCN)=O)CCNC(CCN(CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)=O)NCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.