Fig. 1 · Structure

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STAT3-IN-40

Anti-cancer Agent

STAT3-IN-40 is a potent inhibitor of signal transducer and activator of transcription 3 (STAT3), serving as an anti-cancer agent. By inhibiting both the expression and phosphorylation of STAT3, it triggers immune responses in CD4+ and CD8+ T lymphocytes while inducing ferroptosis and apoptosis in tumor cells. This compound is valuable for research applications focused on developing chemoimmunotherapeutic strategies for cancer treatment.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3053241-01-0
Applications Anti-cancer Agent
Formula C32H34ClN5O12Pt
Molecular Weight 911.18
SMILES
O=C(N1C/C(C(/C(C1)=C/C2=CC=C(C=C2)[N+]([O-])=O)=O)=C\C3=CC=C(C=C3)[N+]([O-])=O)CCCC([O-][Pt+4]45([NH2][C@@]6([H])[C@](CCCC6)([H])[NH2]4)([O-]C(C([O-]5)=O)=O)[Cl-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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