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STAT6-IN-6

STAT6 Inhibitor

STAT6-IN-6 is a selective inhibitor of Signal Transducer and Activator of Transcription 6 (STAT6). It effectively inhibits STAT6 phosphorylation with an IC50 of ≤100 nM, demonstrating minimal impact on phosphorylated STAT3 (IC50 >3 μM). This compound is valuable for research focused on cancer and inflammatory diseases, providing insight into STAT6-mediated pathways and responses.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2952725-20-9
Applications	STAT6 Inhibitor
Formula	C₄₆H₅₇F₂N₄O₈PS₃
Molecular Weight	959.13
SMILES	O=C(N1CC(C2=CC=CC=C2)C(C1)C#N)[C@H]3N4[C@](CCCC[C@@H](C4=O)NC(C5=CC6=CC(C(F)(F)P(OCCSC(CC(C)C)=O)(OCCSC(CC(C)C)=O)=O)=CC=C6S5)=O)([H])CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.