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STF-1623

ENPP1 Inhibitor

STF-1623 is a potent ENPP1 inhibitor with an IC50 of 0.6 nM. By inhibiting ENPP1, STF-1623 activates tumor-specific STING signaling pathways, contributing to the suppression of tumor growth. This compound has demonstrated efficacy in blocking the progression of various cancer types, including breast, pancreatic, colon, and brain cancers, making it a valuable tool for cancer research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2298391-60-1
Applications	ENPP1 Inhibitor
Formula	C₁₆H₂₂N₃O₄P
Molecular Weight	351.34
SMILES	O=P(O)(O)CCC1CCN(C=2N=CN=C3C(OC)=CC=CC32)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.