Fig. 1 · Structure
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STL427944
FOXM1 Inhibitor
STL427944 is a selective inhibitor of the FOXM1 transcription factor, known for its role in regulating cell cycle progression and proliferation. This compound demonstrates significant potential in research applications aimed at overcoming tumor chemoresistance. By targeting FOXM1, STL427944 may provide insights into the molecular mechanisms underlying cancer progression and treatment resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 292028-62-7 |
| Applications | FOXM1 Inhibitor |
| Formula | C25H23N7O4 |
| Molecular Weight | 485.49 |
| SMILES | O=C(C1=CC=CO1)OC2=CC=CC(/C=N/NC3=NC(N4CCOCC4)=NC(NC5=CC=CC=C5)=N3)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.