Fig. 1 · Structure
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Strophanthidin
Cardiac Glycoside
Strophanthidin is a cardiac glycoside that primarily targets the Na+/K+-ATPase enzyme. It exhibits dose-dependent effects, enhancing Na+/K+-ATPase activity at 0.1 and 1 nmol/L concentrations, while inhibiting it at concentrations ranging from 1 to 100 μmol/L. At higher concentrations (10 and 100 nmol/L), it does not alter ATPase activity. Additionally, Strophanthidin significantly increases both diastolic and systolic intracellular Ca2+ concentrations, making it a valuable reagent for studying cardiac contractility and calcium signaling in cardiac research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 66-28-4 |
| Applications | Cardiac Glycoside |
| Formula | C23H32O6 |
| Molecular Weight | 404.50 |
| SMILES | O=C[C@@]12[C@]3([H])[C@](CC[C@@]1(C[C@@H](O)CC2)O)([H])[C@@]4([C@@](C)([C@@H](C5=CC(OC5)=O)CC4)CC3)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.