Fig. 1 · Structure
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SU0268
OGG1 Inhibitor
SU0268 is a selective inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1), a key enzyme involved in the repair of oxidative DNA damage. This compound has been shown to modulate inflammatory responses, particularly during infections caused by Pseudomonas aeruginosa. Its use in research can provide insights into oxidative stress and its role in inflammatory diseases, making it valuable for studying DNA repair mechanisms and host-pathogen interactions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2210228-45-6 |
| Applications | OGG1 Inhibitor |
| Formula | C26H25N3O4S |
| Molecular Weight | 475.56 |
| SMILES | O=C(C1=CC(C2=CC=C(S(=O)(NC3=CC4=C(C=C3)CCCN4C(C5CC5)=O)=O)C=C2)=CC=C1)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.