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CDK2 inhibitor

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Catalog No. A14318

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SU9516 10mg A14318-10

Regular Price: $90.00

Special Price: $81.00

SU9516 25mg A14318-25

Regular Price: $200.00

Special Price: $180.00

SU9516 50mg A14318-50

Regular Price: $320.00

Special Price: $288.00

SU9516 10mM * 1mL in DMSO A14318-10mM-D

Regular Price: $75.00

Special Price: $67.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SU9516 is a potent, selective cdk2 inhibitor. It inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest.


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Chemical Information

Catalog Num A14318
Actions Inhibitor
M. Wt 241.25
Formula C13H11N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 377090-84-1
Synonyms SU 9516, SU-9516

Biological Activity

SU9516 is a potent, selective cdk2 inhibitor. It inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest.
Target Value
CDK2IC50: 22nM
CDK1IC50: 40nM
CDK4IC50: 200nM
PKCIC50: >10μM
p38IC50: >10μM
EGFRIC50: >100μM


Solubility (25°C)* In vitro DMSO 48 mg/mL (198.96 mM)
Water <1 mg/mL (<1 mM)
Ethanol 12 mg/mL heating (49.74 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.45 mL 207.25 mL 414.51mL
0.5 mM 8.29 mL 41.45 mL 82.9 mL
1 mM 4.15 mL 20.73 mL 41.45 mL
5 mM 0.83 mL 4.15 mL 8.29 mL

*The above data is based on the productmolecular weight 241.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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