Total item
Cart Subtotal
$0.00 Biological Activity
SU9516 is a potent, selective cdk2 inhibitor. It inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest.
Targets
| Target | Value |
|---|---|
| CDK2 | IC50: 22nM |
| CDK1 | IC50: 40nM |
| CDK4 | IC50: 200nM |
| PKC | IC50: >10μM |
| p38 | IC50: >10μM |
| PDGFR | IC50: 18μM |
| EGFR | IC50: >100μM |
| In vitro | DMSO | 44 mg/mL (182.38 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 11 mg/mL (45.6 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 41.45 mL | 207.25 mL | 414.51 mL |
| 0.5 mM | 8.29 mL | 41.45 mL | 82.9 mL |
| 1 mM | 4.15 mL | 20.73 mL | 41.45 mL |
| 5 mM | 0.83 mL | 4.15 mL | 8.29 mL |
*The above data is based on the productmolecular weight 241.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14318 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 377090-84-1 |
| Formula | C13H11N3O2 |
| M. Wt | 241.25 |
| Purity | >98% |
| Synonyms | SU 9516, SU-9516 |
| SMILES | COC1=CC\2=C(C=C1)NC(=O)/C2=C\C3=CN=CN3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
PD 0332991 HCl (Palbociclib)
PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activit…
Kenpaullone
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with …
NVP-LCQ195
NVP-LCQ195 is a small molecule heterocyclic inhibitor of CDK1, CDK2, CDK3 and CDK5 with IC50 of 1-42 nM.
BS-181 HCl
BS-181 HCl is a potential anti-tumor agent as CDK7 inhibitor.
BMS-863233 (XL-413)
BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineopla…
R547
R547 is a novel, selective inhibitor of cell cycle and transcriptional cyclin dependent kinases (CDKs) (Ki = 1, 3, and 1 nM for CDK1, CDK2, …
CVT-313
CVT-313 is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 (IC50 = 0.5 uM for Cdk2/A and Cdk2/E; 4.2 uM for Cdk1/B; 2…
PHA-793887
PHA-793887, a novel potent inhibitor of Cdk, target on kinds of cyclin-dependent kinase under low concentrations and poses high activity ag…
Keywords:buy SU9516 | SU9516 Supplier | purchase | cost | manufacturer | order | distributor | buy 377090-84-1| 377090-84-1 Supplier | purchase 377090-84-1 | 377090-84-1 cost | 377090-84-1 manufacturer | order 377090-84-1 | 377090-84-1 distributor
Adooq Quality Guarantee
We promise all products perform as described.