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Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)

Antithrombotic Agent

Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a synthetic hirugen-like peptide with a strong affinity for thrombin, exhibiting a KD of less than 100 nM. This compound functions as an effective antithrombotic agent by inhibiting thrombin-induced fibrin clot formation, with an IC50 value of 0.087 μM. It is suitable for research applications focused on anticoagulation and thrombus-related studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	131791-98-5
Applications	Antithrombotic Agent
Formula	C₆₄H₈₈N₁₀O₂₆S
Molecular Weight	1445.50
SMILES	C([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CCC(O)=O)=O)=O)CCC(O)=O)=O)CCC1)[C@H](CC)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(OS(=O)(=O)O)C=C4)C(N[C@H](C(N[C@H](CCC(O)=O)C(O)=O)=O)CC(C)C)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.