Fig. 1 · Structure

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SufS-IN-1

SufS Inhibitor

SufS-IN-1 is a selective inhibitor of Cysteine desulfurase type II (SufS), specifically designed to covalently bind to the cofactor pyridoxal phosphate (PLP), resulting in stable PLP-ligand conjugates. This compound effectively inhibits SufS activity and is valuable for studying various pathogenic microorganisms, including Plasmodium falciparum, Staphylococcus aureus, and Mycobacterium tuberculosis. Its applications extend to investigations of sulfur metabolism and the development of antimicrobial strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 167933-78-0
Applications SufS Inhibitor
Formula C6H9NO4
Molecular Weight 159.14
SMILES
O=C([C@]1([H])N[C@@]1([H])C(OCC)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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