Fig. 1 · Structure
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Sugammadex
Neuromuscular Block Reversal
Sugammadex is a synthetic γ-cyclodextrin derivative that functions as a reversal agent for neuromuscular blockade. It achieves its effects by encapsulating steroidal neuromuscular blockers, thereby facilitating their rapid clearance from the body. Furthermore, Sugammadex demonstrates nephroprotective properties in the context of ischemia-reperfusion injury, making it valuable in various clinical and research applications related to anesthesia and renal protection.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Blocker |
| CAS Number | 343306-71-8 |
| Applications | Neuromuscular Block Reversal |
| Formula | C72H112O48S8 |
| Molecular Weight | 2002.15 |
| Synonyms | Org25969 free acid |
| SMILES | OC(CCSC[C@@H]1OC(O[C@@H]2[C@H]([C@H](O)C(O[C@H]3[C@H](CSCCC(O)=O)OC(O[C@H]4[C@H](CSCCC(O)=O)OC5[C@@H](O)[C@@H]4O)[C@@H](O)[C@@H]3O)O[C@H]2CSCCC(O)=O)O)[C@@H](O)[C@H](O)[C@H]1OC(O[C@@H](CSCCC(O)=O)[C@H](OC6[C@@H](O)[C@H](O)[C@@H](OC7[C@@H](O)[C@H](O)[C@@H](OC8[C@@H](O)[C@H](O)[C@@H](O5)[C@H](CSCCC(O)=O)O8)[C@H](CSCCC(O)=O)O7)[C@H](CSCCC(O)=O)O6)[C@H]9O)[C@H]9O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.