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Form	MW
Sulcardine This page	459.60
Sulcardine hydrochloride	532.52

Sulcardine

Multi-ion channel Blocker

Sulcardine is a multi-ion channel blocker primarily targeting sodium (INa) and calcium (ICa) channels, exhibiting IC50 values of 26.9 µM and 69.2 µM, respectively. It demonstrates potent inhibition of the hNav1.5 channel and a mild inhibitory effect on hERG channels. Sulcardine is utilized in research investigating anti-arrhythmic effects and the modulation of ion channel activity in cardiac tissue.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Blocker
CAS Number	343935-60-4
Applications	Multi-ion channel Blocker
Formula	C₂₄H₃₃N₃O₄S
Molecular Weight	459.60
SMILES	O=S(NCC1=CC(CN2CCCC2)=C(O)C(CN3CCCC3)=C1)(C4=CC=C(C=C4)OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.