Fig. 1 · Structure
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Sulfamethoxazole-NO
Sulfonamide Immunogen
Sulfamethoxazole-NO (SMX-NO) is a sulfonamide immunogen that plays a critical role in sulfonamide allergy. It induces modest ascorbic acid depletion and forms hemoglobin adducts, while also haptenating tissue proteins. This compound has demonstrated immunogenicity in rodent models, making it a valuable tool for studying allergic responses to sulfonamides and understanding drug hypersensitivity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 29699-89-6 |
| Applications | Sulfonamide Immunogen |
| Formula | C10H9N3O5S |
| Molecular Weight | 283.26 |
| Synonyms | SMX-NO |
| SMILES | O=S(C1=CC=C([N+]([O-])=O)C=C1)(NC2=NOC(C)=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.