Fig. 1 · Structure
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sulfo-DGN462 sodium
DNA-Alkylating Agent
Sulfo-DGN462 sodium is a DNA-alkylating agent that is converted to its active form, DGN462, in culture medium and plasma. DGN462 exhibits potent anti-tumor activity, particularly against acute myeloid leukemia (AML). This compound is valuable for research applications focused on cancer biology and therapeutic development targeting DNA damage in tumor cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1401203-09-5 |
| Applications | DNA-Alkylating Agent |
| Formula | C53H60N5NaO12S2 |
| Molecular Weight | 1046.19 |
| SMILES | O=C(C1=CC(OC)=C2OCC3=CC(N(CC(C)(S)C)CCOCCOCCOC)=CC(COC(C=C(NC[C@@]4([H])N(C5=CC=CC=C5C4)C6=O)C6=C7)=C7OC)=C3)N(C8=CC=CC=C8C9)[C@]9([H])C(NC1=C2)[S](=O)(O[Na])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.