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Sulfo-PDBA-DM4

Drug-Linker Conjugate

Sulfo-PDBA-DM4 is a drug-linker conjugate designed for targeted therapy, incorporating the potent tubulin inhibitor DM4 and the glutathione-cleavable linker Sulfo-PDBA. This conjugate facilitates the formation of antibody-drug conjugates (ADCs), enhancing selective cytotoxicity in cancer treatment. Its unique properties make it a valuable tool in drug delivery and therapeutic research, with potential applications in overcoming drug resistance in tumor cells.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1461704-01-7
Applications	Drug-Linker Conjugate
Formula	C₄₂H₆₀ClN₃O₁₅S₃
Molecular Weight	978.58
SMILES	C[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCC(C)(C)SSCCC(C(O)=O)S(=O)(O)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.