Documents & Downloads

Sulfonadyn-47

GTP-competitive Dynamin I Inhibitor

Sulfonadyn-47 is a GTP-competitive inhibitor of dynamin I that specifically targets the GTPase domain's active site. It demonstrates IC50 values of 3.5 μM against dynamin I, along with 27.3 μM in clathrin-mediated endocytosis assays and 12.3 μM in synaptic vesicle endocytosis assays. This compound has been shown to increase seizure threshold, making it valuable for research focused on seizure mechanisms and potential therapeutic interventions in epilepsy.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3064686-59-2
Applications	GTP-competitive Dynamin I Inhibitor
Formula	C₂₂H₂₃BrN₂O₂S
Molecular Weight	459.40
SMILES	BrC1=CC=C(C=C1)/C=C/CNCCCNS(=O)(C2=C3C=CC=CC3=CC=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.