Fig. 1 · Structure
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SUVN-911
α4β2 Antagonist
SUVN-911 is a select, potent antagonist of the neuronal nicotinic acetylcholine α4β2 receptor, demonstrating a Ki of 1.5 nM and capable of effective brain penetration. This compound shows promising antidepressant activity and is valuable for research applications targeting mood disorders and neuropharmacology. Its oral bioavailability further enhances its utility in preclinical studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2414674-71-6 |
| Applications | α4β2 Antagonist |
| Formula | C11H14Cl2N2O |
| Molecular Weight | 261.15 |
| SMILES | ClC1=NC=C(OC[C@H]2N[C@@H]3C[C@@H]3C2)C=C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.