Fig. 1 · Structure

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SV 156

D2R Antagonist

SV 156 is a highly selective antagonist of the D2 dopamine receptor, exhibiting a Ki value of 2.5 nM for human D2 receptors. With approximately 40-fold selectivity for the D2 receptor over the D3 subtype, SV 156 is primarily utilized in research related to L-DOPA-associated abnormal involuntary movements (AIMs). This compound serves as a valuable tool for investigating the mechanisms underlying dopaminergic signaling and movement disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 873445-60-4
Applications D2R Antagonist
Formula C21H23BrN2O2
Molecular Weight 415.32
SMILES
OC1(C2=CC=C(Br)C=C2)CCN(CC3=CNC4=C3C=C(OC)C=C4)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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