SWS1

Catalog No.: A35763
PD-1/PD-L1 Inhibitor
SWS1 is a d-(+)-biotin-conjugated inhibitor of PD-L1 with an IC50 of 1.8 nM. It has demonstrated significant anticancer activity by enhancing tumor-infiltrating lymphocyte populations and inducing anti-tumor effects in the B16-F10 mouse model, achieving a tumor growth inhibition rate of 66.1%. SWS1 is suitable for research applications focused on immunotherapy and tumor microenvironment studies.
Grouped product items
Size Price Stock Qty
25mg
$1,530.00
In stock
50mg
$1,950.00
In stock
100mg
$2,480.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSWS1 is a d-(+)-biotin-conjugated inhibitor of PD-L1 with an IC50 of 1.8 nM. It has demonstrated significant anticancer activity by enhancing tumor-infiltrating lymphocyte populations and inducing anti-tumor effects in the B16-F10 mouse model, achieving a tumor growth inhibition rate of 66.1%. SWS1 is suitable for research applications focused on immunotherapy and tumor microenvironment studies.
Product Information
Catalog NumA35763
FormulaC47H53ClN6O5S
Molecular Weight849.48
CAS Number2922115-32-8
SMILESO=C(C1N(CCCC1)CC2=C(C=C(C(Cl)=C2)OCC3=C(C(C4=CC=CC=C4)=CC=C3)C)OCC5=CC(C#N)=CC=C5)NCCNC(CCCC[C@H]6[C@]7([H])[C@](NC(N7)=O)([H])CS6)=O
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