Fig. 1 · Structure
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Synthalin hydrochloride
iGluR
Synthalin hydrochloride is a selective inhibitor of ionotropic glutamate receptors (iGluR) with a primary mechanism targeting K+ channels to modulate neuronal excitability. It influences NMDA receptor-mediated depolarization, likely via receptor-associated modulation of L-glutamate and serotonin (5-HT) signaling pathways. This reagent is valuable in research applications focused on elucidating the dynamics of membrane potential changes in various neurons and investigating the involvement of polyamines in modulating neuronal excitability.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 301-15-5 |
| Applications | iGluR |
| Formula | C12H30Cl2N6 |
| Molecular Weight | 329.31 |
| SMILES | N=C(NCCCCCCCCCCNC(N)=N)N.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.