Fig. 1 · Structure
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Synucleozid hydrochloride
SNCA Translation Blocker
Synucleozid hydrochloride is a specific inhibitor of SNCA mRNA translation, targeting the 5′ UTR at the iron response element (IRE) site. This compound effectively reduces the levels of SNCA mRNA associated with polysomes, thereby inhibiting the production of α-synuclein protein. Synucleozid hydrochloride is a valuable tool for studying the molecular mechanisms underlying Parkinson’s disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2741856-68-6 |
| Applications | SNCA Translation Blocker |
| Formula | C22H21ClN6 |
| Molecular Weight | 404.90 |
| Synonyms | NSC 377363 hydrochloride |
| SMILES | N=C(C1=CC2=C(C=C1)C=C(C3=CC=C(NC4=CC=C(C(N)=N)C=C4)C=C3)N2)N.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.