Fig. 1 · Structure
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T-3256336
cIAP1/XIAP Inhibitor
T-3256336 is a potent and orally bioavailable inhibitor of cellular inhibitor of apoptosis protein 1 (cIAP1) and X-linked inhibitor of apoptosis protein (XIAP), displaying IC50 values of 1.3 nM and 200 nM, respectively. This compound exhibits significant anti-tumor activity, making it a valuable tool for research involving apoptosis regulation and potential cancer therapies. Its selective inhibition of cIAP1 and XIAP positions T-3256336 as a candidate for studies targeting apoptotic pathways in various malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1266227-69-3 |
| Applications | cIAP1/XIAP Inhibitor |
| Formula | C31H45F2N5O5 |
| Molecular Weight | 605.72 |
| SMILES | O=C([C@H]1N(C([C@H](C2CCC(F)(F)CC2)NC([C@@H](NC)C)=O)=O)C[C@](C[C@@H](OCC)C3)([H])N3C1)N[C@@H]4CCOC5=CC=CC=C45 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.