T-3775440 hydrochloride

Catalog No.: A18340

LSD1 inhibitor

T-3775440 hydrochloride

T-3775440 hydrochloride Chemical Structure

CAS NO. 1422535-52-1

T-3775440 (hydrochloride) is an irreversible lysine-specific histone demethylase (LSD1) inhibitor with an IC50 value of 2.1 nM.

Availability: In stock

Package Price Qty
5 mg
$380.00
10 mg
$680.00
50 mg
$1,980.00
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Biological Activity

T-3775440 (hydrochloride) is an irreversible lysine-specific histone demethylase (LSD1) inhibitor with an IC50 value of 2.1 nM.
In vitro DMSO 66 mg/mL (190.28 mM)
Water 21 mg/mL (60.54 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.83 mL 144.15 mL 288.31 mL
0.5 mM 5.77 mL 28.83 mL 57.66 mL
1 mM 2.88 mL 14.42 mL 28.83 mL
5 mM 0.58 mL 2.88 mL 5.77 mL

*The above data is based on the productmolecular weight 346.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18340
Actions Inhibitor
CAS No. 1422535-52-1
Formula C18H23ClN4O
M. Wt 346.85
Purity >98%
Synonyms T-3775440 HCl; T 3775440 HCl; T3775440 HCl;
SMILES O=C(C1=CN(C)N=C1)NC2=CC=C([[email protected]]3[[email protected]](NCC4CC4)C3)C=C2.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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