T-448

Catalog No.: A21959

LSD1 inhibitor

T-448

T-448 Chemical Structure

CAS NO. 1597426-53-3

T-448 is a specific and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM.

Availability: In stock

Package Price Qty
1 mg
$495.00
5 mg
$1,485.00
10 mg
$2,530.00
50 mg
$7,590.00
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Biological Activity

T-448 is a specific and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.87 mL 129.37 mL 258.73 mL
0.5 mM 5.17 mL 25.87 mL 51.75 mL
1 mM 2.59 mL 12.94 mL 25.87 mL
5 mM 0.52 mL 2.59 mL 5.17 mL

*The above data is based on the productmolecular weight 386.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21959
Actions Inhibitor
CAS No. 1597426-53-3
Formula C17H20N4OS.1/2C4H4O4
M. Wt 386.5
Solubility DMSO
Purity >98%
Synonyms T448, T 448
SMILES O=C(NC1=NN=C(C)S1)C2=CC=CC([[email protected]]3[[email protected]](NC4CCC4)C3)=C2.O=C(O)/C=C/C(O)=O.[1/2]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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