Fig. 1 · Structure
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T-Cadinol
Sesquiterpene
T-Cadinol is a sesquiterpene derived from Cupressus sylvestris, known for its anti-Trypanosoma cruzi activity. It demonstrates potent efficacy with IC50 values of 18.2 μM and 15.8 μM against the trypomastigote and amastigote forms, respectively. The compound induces mitochondrial damage in parasites, resulting in membrane hyperpolarization and reduced reactive oxygen species levels. T-Cadinol is relevant for research focused on Chagas disease and its treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 5937-11-1 |
| Applications | Sesquiterpene |
| Formula | C15H26O |
| Molecular Weight | 222.37 |
| SMILES | CC([C@H]1[C@@]2([H])[C@](CCC(C)=C2)([H])[C@@](O)(CC1)C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.